Pain Modulation (Gate Control Theory)
TENS therapy stimulates large nerve fibers, specifically A-beta fibers. The electrical stimulation decreases the pain signals that travel along the smaller nerve fibers. Thus, it reduces the pain signals that reach the brain.
This process is called "closing the gate or gate control theory." It essentially means fewer pain signals reach the brain, leading to a decreased pain perception.
Endogenous Opioid Release
E-stim can also promote the release of opioid peptides, known as neurotransmitters, in the nervous system and brain. These neurotransmitters function as natural painkillers in the body.
Studies indicate that the body produces these neurotransmitters in response to specific stimuli, such as e-stim. A systematic review in Medicina found that high-frequency TENS increases endorphin levels in the spinal fluid of participants.
Muscle Contraction
E-stim delivers an electrical impulse that stimulates the motor neurons. Thus, leading to muscle contraction that mimics a natural contraction. Neuromuscular electrical stimulation (NMES) for muscle strengthening after surgery is an example of e-stim-induced muscle contraction.
Improved Circulation
E-stim may also lead to blood vessel dilation, which means the vessels widen. This increases blood flow and improves circulation to the treated area, which helps promote healing.
For instance, a small study published in Open Medicine involved 45 healthy adults who received e-stim for 20 minutes. Researchers used ultrasound to check blood flow. They measured blood vessel size and speed before, right after, and 30 minutes after e-stim. Researchers found that blood flow velocity increased significantly immediately and 30 minutes after administering electrical muscle stimulation.